Drug Detection Time

DrugCut-off Level (EIA)Urine Detection TimeSaliva Detection Time
Amphetamine (AMP)1,000 ng/ml2-4 days1-3 days
Barbiturates (BAR)200 ng/ml2-4 days for short acting; up to 30 days for long acting
Benzodiazepines (BZO)200 ng/ml3-7 days
Cocaine (COC)300 ng/ml1-3 days1-3 days
Ecstasy (MDMA)500 ng/ml1-3 days
Methadone (MTD)300 ng/ml2-4 days
Methamphetamine (MET)1,000 ng/ml2-4 days1-3 days
Opiates (OPI)300 ng/ml2-4 days1-3 days
Oxycodone (OXY)300 ng/ml2-4 days
Phencyclidine (PCP)25 ng/ml2-7 days for casual use; up to 30 days for chronic use1-3 days
Marijuana (THC)50 ng/ml1-3 days for casual use; up to 30 days for chronic use6-12 hours
Tricyclic Antidepressants (TCA)1000 ng/ml7-10 days

BenzodiazepinesEstimated Window of Detection
Short acting (e.g., triazolam)Up to 24 hours
Intermediate acting (e.g., alprazolam, clonazepam,
lorazepam, temazepam)
1 - 12.5 days
Long acting (diazepam)5 - 8 days for diazepam
6 - 24 days for active metabolite, nordiazepam
Chronic abuse of benzodiazepinesUp to 30 days after the last dose

* Higher doses and some pathologies may extend the window of detection. Source: White & Black (2007)


Normal Characteristics of a Urine Specimen
Temperature within 4 minutes of voiding90F to 100F
pH4.5 to 8.0
Urinary Creatinine>20 mg./dl
Specific Gravity>1.003